F-001

Fentanyl-D₅ solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₂₂D₅H₂₃N₂O
• CAS Number: 118357-29-2
• Molecular Weight: 341.50
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• concentration: 100 μg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• storage temp.: -10 to -25°C
• SMILES string: [2H]c1c([2H])c([2H])c(c([2H])c1[2H])N(C2CCN(CC2)CCc3ccccc3)C(=O)CC
• InChI: 1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3/i4D,7D,8D,11D,12D
• InChI key: PJMPHNIQZUBGLI-SCUSKTIWSA-N

Description

General description

An internal standard suitable for fentanyl testing or isotope dilution methods by GC/MS or LC/MS for clinical toxicology, urine drug testing, pain prescription monitoring, or forensic analysis. Fentanyl is a potent synthetic narcotic analgesic and local anesthetic sold under various trade names including Sublimaze, Duregesic, Actiq^®, and Fentora^®.

Application

• Fentanyl-D₅ analytical standard: Stability and compatibility of an intramuscular fetal anesthetic cocktail, which includes Fentanyl-D₅, were studied for fetal intervention. This highlights Fentanyl-D₅′s role as a reliable analytical standard in the preparation of precise medication dosages essential for sensitive applications (Ross et al., 2024).


• Opioid research chemical: Fentanyl-D₅ was used in developing a method for quantifying nitazene analogs in Dried Blood Spots using liquid chromatography-tandem mass spectrometry, underlining its importance as a research chemical in the study of synthetic opioids (Ververi et al., 2024).


• Mass spectrometry Fentanyl: The determination of nine fentanyl drugs in hair samples by GC-MS/MS and LC-MS/MS employed Fentanyl-D₅, showcasing its critical application in forensic toxicology and pharmacokinetic studies to track opioid exposure (Wei and Su, 2022).


• Synthetic opioid calibration solution: A novel bioanalytical method determined opioids in blood and pericardial fluid, utilizing Fentanyl-D₅ as part of the calibration solution. This study highlights its pivotal role in enhancing the reliability of quantitative toxicological analysis (Ferreira et al., 2020).

Legal Information

Actiq is a registered trademark of Anesta Corp.

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Fentora is a registered trademark of Cima Labs, Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup