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Key Documents

M-009

Supelco

(±)-Methamphetamine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C10H15N
CAS Number:
Molecular Weight:
149.23
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

CC(NC)CC1=CC=CC=C1

InChI

1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3

InChI key

MYWUZJCMWCOHBA-UHFFFAOYSA-N

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General description

Methamphetamine is a psychostimulant drug of the phenethylamine and amphetamine classes known by the street names "meth," "ice," and "glass". This Snap-N-Spike® reference solution is applicable for use in LC/MS or GC/MS applications such as clinical toxicology, sports testing, forensic analysis, or urine drug testing. The dextrorotatory isomer of methamphetamine is a pharmaceutical drug sold under the trade name Desoxyn® for treatment of ADHD and obesity.

Application


  • Modeling methamphetamine use disorder and relapse in animals: short- and long-term epigenetic, transcriptional, and biochemical consequences in the rat brain: This research explores the utility of (±)-Methamphetamine in neurochemical studies, specifically examining its epigenetic, transcriptional, and biochemical impacts on the rat brain over short and long periods. The study underscores the importance of methamphetamine as a research chemical in understanding addiction and relapse mechanisms (Elhadi K, et al., 2023).

  • Vaccines as Immunotherapies for Substance Use Disorders: This review highlights innovative approaches using (±)-Methamphetamine in the development of vaccines aimed at treating substance use disorders. It exemplifies cutting-edge pharmaceutical applications in creating immunotherapies to combat addiction (Kosten TR, 2024).

  • The reflections of health service providers on implementing contingency management for methamphetamine use disorder in Australia: This article discusses the practical applications of (±)-Methamphetamine in contingency management strategies for treating methamphetamine use disorders, reflecting on real-world challenges and solutions from healthcare providers (Clay S, et al., 2024).

  • Correction: PrEP Uptake and Methamphetamine Use Patterns in a 4-Year U.S. National Prospective Cohort Study of Sexual and Gender Minority People, 2017-2022: This correction notice relates to a study that investigates patterns of methamphetamine use and its implications in public health, especially in preventive medicine strategies among sexual and gender minority groups (Guo Y, et al., 2024).

  • Identification of the circRNA-miRNA-mRNA network for treating methamphetamine-induced relapse and behavioral sensitization with cannabidiol: This research demonstrates the use of (±)-Methamphetamine to explore the genomic and molecular pathways involved in drug addiction and relapse, offering insights into potential treatments using cannabidiol (Liu L, et al., 2024).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Desoxyn is a registered trademark of Abbott Laboratories Corp.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Emily E Reichard et al.
Pharmaceutical research, 33(12), 2954-2966 (2016-11-04)
Methamphetamine (METH) abuse is a worldwide drug problem, yet no FDA-approved pharmacological treatments are available for METH abuse. Therefore, we produced an anti-METH single chain antibody fragment (scFv7F9Cys) as a pharmacological treatment for METH abuse. ScFv's have a short half-life

Protocols

In this study, optimized methods are presented for sample preparation and chiral chromatography for the LC/MS analysis of amphetamine and methamphetamine enantiomers in urine.

Optimized sample prep and chiral chromatography methods for the LC/MS analysis of these drug enantiomers in urine

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