K2755
2-Keto-3-deoxyoctonate ammonium salt
≥97%
Synonym(s):
3-Deoxyoctulosonic acid, KDO
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About This Item
Linear Formula:
C8H14O8 · NH3
CAS Number:
Molecular Weight:
255.22
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
≥97%
form
powder
storage temp.
−20°C
SMILES string
N.OCC(O)C1OC(O)(CC(O)C1O)C(O)=O
InChI
1S/C8H14O8.H3N/c9-2-4(11)6-5(12)3(10)1-8(15,16-6)7(13)14;/h3-6,9-12,15H,1-2H2,(H,13,14);1H3
InChI key
UDJBBKGYARWWNJ-UHFFFAOYSA-N
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Application
- Synthesis of KDO Analogues: A significant study focused on the synthesis of analogues of 3-deoxy-D-manno-octulosonic acid (KDO), which includes compounds such as 2-Keto-3-deoxyoctonate ammonium salt. These analogues were evaluated as potential inhibitors of CMP-KDO synthetase, playing a critical role in the development of new therapeutic agents targeting bacterial infections and enhancing understanding of bacterial lipopolysaccharide synthesis (Luthman et al., 1987).
Biochem/physiol Actions
KDO is a sialic acid that is a component of bacterial lipopolysaccharides and a possible target for antibiotic development.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Articles
Review article and products for sialic acid synthesis and signaling.
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