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764620

Sigma-Aldrich

Poly(D,L-lactide)

average Mn 10,000, PDI ≤1.2

Synonym(s):

PDLA, PLA, polyDL-lactide

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About This Item

UNSPSC Code:
12162002
NACRES:
NA.23

form

solid

optical activity

[α]/D 0°, c = 0.5% in chloroform

mol wt

average Mn 10,000

degradation timeframe

<6 months

mp

287-293 °C

PDI

≤1.2

storage temp.

2-8°C

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Application

Used in Drug Delivery including coating nanoparticles1. Can be end-group functionalizated2 or used as a macroinitiator/block precursor3.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Wolf, Florian F.; et al.
Macromolecules, 42, 5622-5628 (2009)
Zhang, Wen-Bin; et al.
Macromolecules, 44, 2589-2596 (2011)
Preparation of Protein-Loaded Poly(L-Lactide) Microspheres by Solution-Enhanced Dispersion by Supercritical CO2
Chen A Z, et al.
Journal of Biomimetics, Biomaterials, and Tissue Engineering, 11, 93-100 (2011)

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Biodegradable Polyester Based Nanoparticle Formation by Miniemulsion Technique

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

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