09-066

Anti-ASPM Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): Abnormal spindle protein homolog, Asp homolog, asp (abnormal spindle) homolog, microcephaly associated (Drosophila), asp (abnormal spindle)-like, microcephaly associated, asp (abnormal spindle)-like, microcephaly associated (Drosophila), microcephaly, pr
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: rat, human
• species reactivity (predicted by homology): chimpanzee, primate
• technique(s): ELISA: suitable; immunohistochemistry: suitable
• NCBI accession no.: NP_060606
• UniProt accession no.: Q8IZT6
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... ASPM(259266)

Description

General description

The ASPM gene is the human ortholog of the Drosophila melanogaster ′abnormal spindle′ gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts (Bond et al., 2002 [PubMed 12355089]). The mouse gene ASPM is expressed specifically in the primary sites of prenatal cerebral cortical neurogenesis.

Specificity

This antibody recognizes ASPM.

Immunogen

KLH-conjugated linear peptide corresponding to human ASPM.

Application

Anti-ASPM Antibody detects level of ASPM & has been published & validated for use in IH, ELISA.

ELISA: Tested in direct ELISA against the ASPM immunogen.

Research Category
Signaling

Research Sub Category
Cell Cycle, DNA Replication & Repair

Quality

Immunohistochemistry Analysis: 1:300 dilution of this antibody detected ASPM in human ductal carcinoma tissue.

Target description

218, 95, 75 kDa Observed UniProtKB/Swiss-Prot entry Q8IZT6 describes 2 isoforms produced by alternative splicing: Isoform 1 at 409.800kDa and Isoform 2 at 217.794kDa Multiple other isoforms in ref: Human Molecular Genetics, 2005, Vol. 14, No. 15 2155–2165.

Physical form

Affinity purified

Purified rabbit serum in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Human ductal carcinoma tissue

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable