1045520

Azacitidine

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: 5-Azacytidine, 4-Amino-1-(β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one, Ladakamycin
• Fórmula empírica (notación de Hill): C₈H₁₂N₄O₅
• Número de CAS: 320-67-2
• Peso molecular: 244.20
• Beilstein: 620461
• Número MDL: MFCD00006539
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329749084
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: azacitidine
• fabricante / nombre comercial: USP
• mp: 226-232 °C (dec.) (lit.)
• aplicaciones: pharmaceutical (small molecule)
• formato: neat
• cadena SMILES: NC1=NC(=O)N(C=N1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O
• InChI: 1S/C8H12N4O5/c9-7-10-2-12(8(16)11-7)6-5(15)4(14)3(1-13)17-6/h2-6,13-15H,1H2,(H2,9,11,16)/t3-,4-,5-,6-/m1/s1
• Clave InChI: NMUSYJAQQFHJEW-KVTDHHQDSA-N
• Información sobre el gen: human ... DNMT1(1786) , DNMT3A(1788)

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Azacitidine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Acciones bioquímicas o fisiológicas

A potent growth inhibitor and cytotoxic agent; inhibits DNA methyltransferase, an important regulatory mechanism of gene expression, gene activation and silencing.

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08,GHS07,GHS09
• Palabra de señalización: Danger
• Frases de peligro: H302,H341,H350,H360FD,H372,H410
• Consejos de prudencia: P202 - P260 - P264 - P273 - P301 + P312 - P308 + P313
• Clasificaciones de peligro: Acute Tox. 4 Oral - Aquatic Chronic 1 - Carc. 1A - Muta. 2 - Repr. 1B - STOT RE 1
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3