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1012032

USP

Actein

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

Shengmating

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About This Item

Fórmula empírica (notación de Hill):
C37H56O11
Número de CAS:
18642-44-9
Peso molecular:
676.83
Número MDL:
MFCD25371991
Código UNSPSC:
41116107
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

actein

fabricante / nombre comercial

USP

aplicaciones

pharmaceutical (small molecule)

Formato

neat

cadena SMILES

C[C@@H]1C[C@@]2([C@H]3[C@@](O3)(C)[C@@H](O)O2)O[C@]4([H])[C@@]1([H])[C@]([C@H](OC(C)=O)C[C@]5(C6)[C@@]7([H])CC[C@]8([H])[C@]56CC[C@H](O[C@]9([H])OC[C@@H](O)[C@H](O)[C@H]9O)C8(C)C)(C)[C@@]7(C)C4

InChI

1S/C35H54O9/c1-17-13-35(27-32(6,43-27)28(39)44-35)42-19-14-31(5)21-8-7-20-29(2,3)22(41-26-25(38)24(37)18(36)15-40-26)9-10-33(20)16-34(21,33)12-11-30(31,4)23(17)19/h17-28,36-39H,7-16H2,1-6H3/t17-,18-,19+,20+,21+,22?,23+,24+,25-,26+,27+,28?,30-,31+,32-,33-,34+,35?/m1/s1

Clave InChI

RKNTVINERUAWJC-LXVMFROXSA-N

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Actein USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Black Cohosh
  • Black Cohosh Fluidextract
  • Black Cohosh Tablets
  • Powdered Black Cohosh
  • Powdered Black Cohosh Extract

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Serhat S Cicek et al.
Journal of natural products, 73(12), 2024-2028 (2010-11-19)
Black cohosh (Actaea racemosa) is a frequently used herbal remedy for the treatment of mild climacteric symptoms. In the present study, the modulation of γ-aminobutryic acid (GABA)-induced chloride currents (I(GABA)) through GABA type A (GABA(A)) receptors by black cohosh extracts
M Koeda et al.
Chemical & pharmaceutical bulletin, 43(5), 771-776 (1995-05-01)
Three new cyclolanostanol xylosides were isolated from a batch of commercial Cimicifuga Rhizome, cimicifugoside H-1 (1), C35H52O9, mp 260-262 degrees C, [alpha]D -43.5 degrees, cimicifugoside H-2 (2), C35H54O10, mp 227-229 degrees C, [alpha]D -38.8 degrees, and cimicifugoside H-5 (3), C35H52O10
Linda Saxe Einbond et al.
Anticancer research, 27(2), 697-712 (2007-05-01)
Previous studies indicate that specific extracts and the pure triterpene glycoside actein obtained from black cohosh inhibit growth of human breast cancer cells. Our aim is to identify alterations in gene expression induced by treatment with a methanolic extract (MeOH)
Linda Saxe Einbond et al.
Biochemical and biophysical research communications, 375(4), 608-613 (2008-08-30)
The Na+K+-ATPase is a known target of cardiac glycosides such as digitoxin and ouabain. We determined that the enzyme also is a target of the structurally-related triterpene glycoside actein, present in the herb black cohosh. Actein's inhibition of Na+-K+-ATPase activity
Linda Saxe Einbond et al.
International journal of cancer, 121(9), 2073-2083 (2007-07-11)
Previous studies indicate that the triterpene glycoside actein from the herb black cohosh inhibits growth of human breast cancer cells. This study seeks to identify genes altered in human breast cancer cells by treatment with actein, using gene expression analysis.
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