PHL89159

Apigenin

phyproof^® Reference Substance

• Sinónimos: 4′,5,7-Trihydroxyflavone, 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone
• Fórmula empírica (notación de Hill): C₁₅H₁₀O₅
• Número de CAS: 520-36-5
• Peso molecular: 270.24
• Beilstein: 262620
• Número MDL: MFCD00006831
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: primary reference standard
• Línea del producto: phyproof^® Reference Substance
• Análisis: ≥95.0% (HPLC)
• formulario: powder
• fabricante / nombre comercial: PhytoLab
• mp: >300 °C (lit.)
• cadena SMILES: Oc1ccc(cc1)C2=CC(=O)c3c(O)cc(O)cc3O2
• InChI: 1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H
• Clave InChI: KZNIFHPLKGYRTM-UHFFFAOYSA-N

Descripción

Descripción general

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Acciones bioquímicas o fisiológicas

A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G₂/M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appear to be related to induction of p53. Inhibits PMA-mediated tumor promotion by inhibiting protein kinase C and the resulting suppression of oncogene expression. It has also been reported to inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.

Otras notas

This compound is commonly found in plants of the genus: achillea mentha pimpinella primula salvia silybum thymus

Información legal

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Información de seguridad

• Código de clase de almacenamiento: 13 - Non Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3