U1006

Uridine 5′-triphosphate trisodium salt solution

HPLC purified, aqueous solution for RNA polymerase transcription

• Sinónimos: UTP
• Número MDL: MFCD00044310
• Código UNSPSC: 41106305
• ID de la sustancia en PubChem: 24900622
• NACRES: NA.52

Propiedades

• origen biológico: yeast (Candida Utilis)
• Nivel de calidad: 300
• Ensayo: ≥95 (HPLC)
• Formulario: liquid
• concentración: 100 mM in H₂O (adjusted to pH 7 with Trizma^®; base)
• color: colorless
• actividad extraña: DNase and RNase, none detected
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• cadena SMILES: [Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1
• Clave InChI: MMJGIWFJVDOPJF-LLWADOMFSA-K
• Información sobre el gen: human ... P2RY2(5029) ; rat ... P2ry2(29597)

Descripción

Aplicación

Uridine 5′-triphosphate trisodium salt solution has been used to increase the intracellular Ca²⁺ levels in rat primary tracheal epithelial cells. It has also been used as a nucleotide substrate to analyze the activity of MutT homologue 1 (MTH1).

Acciones bioquímicas o fisiológicas

P2Y receptor agonist

UTP plays a crucial role in the process of transcription by participating in the synthesis of RNA. It is associated with glycogen synthesis, protein glycosylation, and membrane phospholipid biosynthesis. UTP is involved in the production of ATP, which is essential for metabolic reactions.

Uridine 5′-triphosphate (UTP) is released during nerve injury and acts as an agonist of the purinergic P2Y2 receptors present on the surface of Schwann cells.

Información legal

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable