T0951
Anti-Tet Repressor (TETR) antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
Sinónimos:
Anti-Tetracycline Repressor Protein
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About This Item
Productos recomendados
origen biológico
rabbit
Nivel de calidad
conjugado
unconjugated
forma del anticuerpo
affinity isolated antibody
tipo de anticuerpo
primary antibodies
clon
polyclonal
Formulario
buffered aqueous solution
mol peso
antigen ~22 kDa by calculation
reactividad de especies
human
técnicas
indirect ELISA: suitable
western blot: 1:1,000
Condiciones de envío
dry ice
temp. de almacenamiento
−20°C
modificación del objetivo postraduccional
unmodified
Categorías relacionadas
Descripción general
Tet Repressor (TETR) is homodimer comprising a C-terminal helix-turn-helix motif (HTH) and N-terminal DNA-binding domain,. It also has a C-terminal tetracycline-binding and dimerization (TBD) domain.
Inmunógeno
Anti-Tet Repressor (TETR) reacts with amino acid residues 31-49 (AQKLGVEQPTLYWHVKNKR) of 22 kDa Tet repressor protein
Aplicación
Anti-Tet Repressor (TETR) antibody produced in rabbit has been used in western blotting.
Acciones bioquímicas o fisiológicas
The Tet system is employed in conditional gene expression studies in eukaryotic cells. TetR ( can be used for such applications in some organisms without further modifications. In mammals and in a large variety of other organisms, however, eukaryotic transcriptional activator or repressor domains are fused to TetR to turn it into an efficient regulator. TetR interaction with antibiotic tetracyclin decreases its binding affinity to DNA.
Forma física
Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
nwg
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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The TetR family of transcriptional repressors
Ramos JL, et al.
Microbiology and Molecular Biology Reviews, 69(2), 326-356 (2005)
E Pook et al.
European journal of biochemistry, 258(3), 915-922 (1999-02-17)
We isolated five monoclonal antibodies (mAbs) made against tetracycline repressor (TetR), one against the TetR tetracycline complex (Tc) and two against the TetR-tet operator (tetO) complex. The epitopes of the anti-TetR mAbs are localized in the alpha-helix-turn-alpha-helix motif (HTH), at
FOXO1 is an essential regulator of pluripotency in human embryonic stem cells
Zhang X, et al.
Nature Cell Biology, 13(9), 1092-1092 (2011)
W Hillen et al.
Annual review of microbiology, 48, 345-369 (1994-01-01)
Tetracycline-resistance determinants encoding active efflux of the drug are widely distributed in gram-negative bacteria and unique with respect to genetic organization and regulation of expression. Each determinant consists of two genes called tetA and tetR, which are oriented with divergent
The application of Tet repressor in prokaryotic gene regulation and expression
Bertram R and Hillen W
Microbial Biotechnology, 1(1), 2-16 (2008)
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