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Merck
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Key Documents

SRP4145

Sigma-Aldrich

IL-6 from rat

recombinant, expressed in E. coli, ≥90% (SDS-PAGE), ≥90% (HPLC)

Sinónimos:

B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, IFN-b2, MGI-2

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About This Item

Número MDL:
Código UNSPSC:
12352202
NACRES:
NA.32

origen biológico

rat

recombinante

expressed in E. coli

Análisis

≥90% (HPLC)
≥90% (SDS-PAGE)

formulario

lyophilized

potencia

<0.01 ng/mL ED50

mol peso

~21.7 kDa

envase

pkg of 10 μg

impurezas

endotoxin, tested

Nº de acceso NCBI

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

Información sobre el gen

rat ... Il6(24498)

Descripción general

Interleukin- 6 (IL-6) is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. It is a pro-inflammatory cytokine. IL-6 originates from mononuclear phagocytes, T and B lymphocytes, vascular endothelial cells and fibroblasts. It has a role in various physiological and pathological processes. IL-6 plays an important role in intracellular signaling pathways. Recombinant rat IL-6 is a 21.7kDa protein containing 187 amino acid residues.

Forma física

Lyophilized without any additives.

Reconstitución

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in 10 mM HCl to a concentration of 0.1-1.0 μg/μL. The solution can then be diluted into other aqueous buffers.

Certificados de análisis (COA)

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It has been shown that Faecalibacterium prausnitzii (F. prausnitzii), one of the dominant intestinal bacterial flora, may protect colonic mucosa against the development of inflammation and subsequent inflammatory bowel disease (IBD), with the underlying mechanisms being unclear. The impacts of

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