SBR00067

Rifampicin Water Soluble

solubility: 50 mg/mL in water, freely soluble

• Código UNSPSC: 51283601
• NACRES: NA.76

Propiedades

• Formulario: solid
• Nivel de calidad: 200
• actividad específica: (Antibacterial)
• solubilidad: water: freely soluble 50 mg/mL
• espectro de actividad antibiótica: Gram-negative bacteria; Gram-positive bacteria; mycobacteria; viruses
• Modo de acción: protein synthesis | interferes
• temp. de almacenamiento: −20°C

Descripción

Descripción general

Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections. Rifampicin is widely used as an antipruritic agent in the autoimmune cholestatic liver disease, and primary biliary cirrhosis (PBC). Rifampicin was also found active by inhibiting Tau Oligomer Propagation in Alzheimer’s disease. In addition, Rifampicin is used as a selection agent for agrobacterium mediated plant transformation.

Aplicación

Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections. It is widely used as an antipruritic agent in the autoimmune cholestatic liver disease, primary biliary cirrhosis (PBC). It has been shown to cause hepatitis.

Acciones bioquímicas o fisiológicas

Rifampicin inhibits the assembly of DNA and protein into mature virus particles. It inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase, which results in cell death.

Mode of Action: Inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase. Inhibits the assembly of DNA and protein into mature virus particles.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302
• Consejos de prudencia: P264 - P270 - P301 + P312 - P501
• Clasificaciones de peligro: Acute Tox. 4 Oral
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable