SAB5701923

Anti-Phospho-CDC25A-S76 antibody produced in rabbit

• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: liquid
• reactividad de especies: mouse, rat, human
• concentración: 1.51 mg/mL
• técnicas: western blot: 1:500-1:2000
• Nº de acceso UniProt: P30304
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pSer76)
• Información sobre el gen: human ... CDC25A(993)

Descripción

Descripción general

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

Inmunógeno

A phospho specific peptide corresponding to residues surrounding S76 of human CDC25A

Forma física

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable