SAB5701774

Anti-Phospho-Tyk2-Y1054/1055 antibody produced in rabbit

• Código UNSPSC: 12352203
• NACRES: NA.41
• clon: polyclonal
• application: IHC; WB
• reactividad de especies: mouse, rat, human
• técnicas: immunohistochemistry: 1:50-1:100; immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: liquid
• reactividad de especies: mouse, rat, human
• concentración: 2.37 mg/mL
• técnicas: immunohistochemistry: 1:50-1:100; immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000
• Nº de acceso UniProt: P29597
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pTyr1054/pTyr1055)
• Información sobre el gen: human ... Tyk2(7297)

Descripción

Descripción general

This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

Inmunógeno

A synthetic phosphorylated peptide around Y1054 & Y1055 of human Tyk2 (NP_003322.3).

Forma física

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable