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Key Documents

SAB4700767

Sigma-Aldrich

Monoclonal Anti-HBV antigen HBsAg antibody produced in mouse

clone HB5, purified immunoglobulin, buffered aqueous solution

Sinónimos:

Hbsag Antibody, Hbsag Antibody - Monoclonal Anti-HBV antigen HBsAg antibody produced in mouse

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

mouse

conjugado

unconjugated

forma del anticuerpo

purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

HB5, monoclonal

formulario

buffered aqueous solution

reactividad de especies

hepatitis B virus

concentración

1 mg/mL

técnicas

ELISA: suitable
immunocytochemistry: suitable

isotipo

IgG2a

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

Descripción general

HBsAg is the surface antigen of HBV (hepatitis B virus). It is secreted in the form of pleomorphic particles, mostly spherical and partly filamentous. HBV is usually spread due to percutaneous or mucosal exposure to infected blood and other body fluids.
The antibody HB5 recognizes following Hepatitis B virus (HBV) subtypes: ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq-. Hepatitis B surface antigen (HBsAg) is a marker of infectivity.
Specificity of the antibody HB5 was verified by ELISA on panel of virus subtypes identified on International Workshop on HBsAg Subtypes (Paris, April 1975). The antibody HB5 does not cross-block with the antibody HB3.

Inmunógeno

Purified HbsAg from human plasma.

Aplicación

Monoclonal Anti-HBV antigen HBsAg antibody has been used in quantitative assays.

Acciones bioquímicas o fisiológicas

HBsAg acts as a clinical marker and helps to specify acute or chronic infection. Presence of HBsAg indicates HBV infection. Overexpression of HBsAg is seen in infected hepatocytes.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Hepatitis B and D Protocols (2004)
Palashpriya Das et al.
World journal of hepatology, 12(10), 775-791 (2020-11-18)
The recent rise in the incidence of hepatitis B virus (HBV) infections in a densely populated city of eastern India ("mixing vessel" of people of varied socio-economic and immune status) prompted this study. Applying saliva on fingers for enumerating bank
Establishment of magnetic microparticles-assisted time-resolved fluoroimmunoassay for determinating biomarker models in human serum.
Ren ZQ, et al.
PLoS ONE, 10(6), e0130481-e0130481 (2015)
Global epidemiology of hepatitis B virus infection: new estimates of age-specific HBsAg seroprevalence and endemicity.
Ott JJ, et al.
Vaccine, 30(12), 2212-2219 (2012)
Zhi-Qi Ren et al.
PloS one, 10(6), e0130481-e0130481 (2015-06-24)
In order to early screen and detect suspected biomarkers from pathogens and the human body itself, tracers or reaction strategies that can act as signal enhancers have been proposed forth at purpose. In this paper, we discussed the applicability of

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