SAB4504299

Anti-phospho-Casein Kinase II α (pTyr²⁵⁵) antibody produced in rabbit

affinity isolated antibody

• Código UNSPSC: 12352203
• NACRES: NA.43

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: antigen 45 kDa
• reactividad de especies: human, mouse, rat
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:10000; western blot: 1:500-1:1000
• Nº de acceso NCBI: P68400
• Nº de acceso UniProt: P68400
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pTyr255)
• Información sobre el gen: human ... CSNK2A1(1457)

Descripción

Descripción general

Casein kinase II α(CK2) is a pleiotropic serine/threonine kinase, that is located on human chromosome 16p13. 2-p13. 3.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human Casein Kinase II alpha around the phosphorylation site of Tyr255.

Immunogen Range: 221-270

Acciones bioquímicas o fisiológicas

Casein kinase II α(CK2) regulates T-cell polarization by initiating the activation of dendritic cells. CK2 participates in the development of breast carcinoma. Mutations in CK2 results in neurodevelopmental abnormalities and dysmorphic features. This protein induces prosurvival and proinflammatory signaling pathways.

Características y beneficios

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Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable