SAB4300628

Anti-phospho-CK2α (pThr³⁶⁰/Ser³⁶²) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-CK2A1, Anti-CKII, Anti-CSNK2A1
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: ~42 kDa
• reactividad de especies: human, rat, mouse
• concentración: 1 mg/mL
• técnicas: western blot: 1:500-1:1000
• isotipo: IgG
• secuencia del inmunógeno: (V-P-Tp-P-Sp-P-L)
• Nº de acceso NCBI: NM_001903.2
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pThr360/pSer362)
• Información sobre el gen: human ... CTNNA1(1495)

Descripción

Descripción general

The antibody detects endogenous level of CK2 only when phosphorylated at thronine 360.

Inmunógeno

Peptide sequence around phosphorylation site of threonine360/serine 362 (V-P-Tp-P-Sp-P-L), according to the protein NP_001894.2

Características y beneficios

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Descripción de destino

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha′ chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates ′Ser-392′ of p53/TP53 following UV irradiation.

Forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable