SAB4501295

Anti-GLUR2 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: GluR-2, GluR-B, GluR-K2, Glutamate receptor 2, Glutamate receptor ionotropic
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: antigen 98 kDa
• reactividad de especies: human, mouse, rat
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Nº de acceso NCBI: P42262
• Nº de acceso UniProt: P42262
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... GRIA2(2891)

Descripción

Descripción general

Anti-GLUR2 Antibody detects endogenous levels of total GLUR2 protein.

GLUR2 (glutamate receptor 2) is coded by gria2 gene. It is mapped to human chromosome 4q32. It is abundantly expressed in the brain.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human GluR2.

Immunogen Range: 834-883

Aplicación

Anti-GLUR2, C-Terminal antibody has been used in electron microscopy.

Acciones bioquímicas o fisiológicas

Presence of the glutamate receptor 2 (GluR2) subunit prevents calcium influx through AMPA-receptor complexes. Deletion of this subunit results in enhanced hippocampal long-term potentiation. As such, AMPA receptors play crucial roles in normal neuronal activity, including synaptic plasticity, synaptic scaling, homeostatic synaptic plasticity, learning and memory, as well as in synaptogenesis and the formation of neuronal circuitry.

Características y beneficios

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Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable