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Key Documents

SAB4300959

Sigma-Aldrich

Anti-CTSL antibody produced in rabbit

affinity isolated antibody

Sinónimos:

CATL, CTSL1, MEP

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

formulario

buffered aqueous solution

mol peso

38 kDa

reactividad de especies

mouse, human

concentración

1.8 mg/mL

técnicas

immunohistochemistry: 1:50- 1:200
western blot: 1:500-1:2000 (Cell Lysate)

isotipo

IgG

nº de acceso

NP_001244900.1

Nº de acceso UniProt

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... CTSL(1514)

Especificidad

The antibody detects endogenous levels of total CTSL protein.

Inmunógeno

Fusion protein corresponding to a region derived from internal residues of human cathepsin L

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Opcional

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

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Guo-Xiang Fu et al.
Free radical research, 51(11-12), 932-942 (2017-10-19)
Recent evidence suggests a link between cathepsin L (CTSL) and vascular diseases. However, its contribution to reactive oxygen species (ROS) homeostasis in the vasculature remains unknown. p66shc is a redox enzyme implicated in mitochondrial ROS generation and translation of oxidative
Xinya Xu et al.
Journal of dermatological science, 90(3), 263-275 (2018-03-05)
The deposition of advanced glycation end products (AGEs) is accelerated in photoaged skin, but the underlying mechanisms remain elusive. Intracellular degradation has been recently considered to play an important role in AGEs removal. Although lysosomal cathepsin D (CatD), B (CatB)
Annika K Hult et al.
Transfusion, 58(8), 2036-2045 (2018-10-03)
The FORS histo-blood group system was described in 2013 and much remains to be investigated regarding its genetic and immunohematologic characteristics, as well as its clinical importance. While presence of the c.887G>A-mutated GBGT1 gene, which results in FORS1 glycosphingolipid expression
Mike Flint et al.
Nature communications, 10(1), 285-285 (2019-01-19)
There are no approved therapies for Ebola virus infection. Here, to find potential therapeutic targets, we perform a screen for genes essential for Ebola virus (EBOV) infection. We identify GNPTAB, which encodes the α and β subunits of N-acetylglucosamine-1-phosphate transferase.
Chris W Lee et al.
Molecular neurodegeneration, 12(1), 55-55 (2017-07-27)
Haploinsufficiency of GRN, the gene encoding progranulin (PGRN), causes frontotemporal lobar degeneration (FTLD), the second most common cause of early-onset dementia. Receptor-mediated lysosomal targeting has been shown to regulate brain PGRN levels, and complete deficiency of PGRN is a direct

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