SAB4300883

Anti-NeuN antibody produced in rabbit

affinity isolated antibody

• Sinónimos: FLJ56884, FLJ58356, FOX3, HRNBP3, RBFOX3
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: 34 kDa
• reactividad de especies: human, mouse, rat
• concentración: 1.0 mg/mL
• técnicas: western blot: 1:500-1:2000 (Cell Lysate)
• isotipo: IgG
• nº de acceso: NP_001076044.1
• Nº de acceso UniProt: A6NFN3
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... RBFOX3(146713)

Descripción

Descripción general

NeuN (neuronal nuclei), also known as RBFOX3 (RNA binding protein, fox-1 homolog 3), is encoded by the gene mapped to human chromosome 17q25.3. The encoded protein belongs to the RBFOX family of proteins. NeuN is present in nuclei and perinuclear cytoplasm of most of the neurons in the central nervous system (CNS) of mammals.

Especificidad

The antibody detects endogenous level of total NeuN protein.

Inmunógeno

Recombinant protein of human NeuN.

Aplicación

Anti-NeuN antibody produced in rabbit has been used in Immunohistochemical staining.

Acciones bioquímicas o fisiológicas

NeuN (neuronal nuclei)/RBFOX3 (RNA binding protein, fox-1 homolog 3) is a RNA splicing factor. It controls neuronal splicing pathway. NeuN is used as a potential marker of postmitotic neurons in studies of neuronal differentiation and in the evaluation of neuronal status both in norm and pathology. Mutation in the gene is associated with risk of rolandic epilepsy. Studies have shown that in presence of neurological disorders, the protein is mislocalized.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable