SAB4300627

Anti-CCR7 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-BLR2, Anti-CD197, Anti-CDw197, Anti-CMKBR7, Anti-EBI1
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: ~43 kDa
• reactividad de especies: human
• concentración: 1 mg/mL
• técnicas: western blot: 1:500-1:1000
• isotipo: IgG
• secuencia del inmunógeno: (T-D-D-Y-I)
• Nº de acceso NCBI: NM_001838.3
• Nº de acceso UniProt: P32248
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CCR7(1236)

Descripción

Descripción general

Anti-CCR7 antibody detects endogenous level of total CCR7(CD197) protein. CCR7 (C-C motif chemokine receptor 7) is localized to T cells, natural killer and dendritic cells. The CCR7 gene is mapped to human chromosome 17q21.2.

Inmunógeno

Peptide sequence around aa. 29-33 (T-D-D-Y-I), according to the protein NP_001829.1

Acciones bioquímicas o fisiológicas

CCR7 (C-C motif chemokine receptor 7) regulates lymphocyte cell trafficking and lymph node distribution. CCR7′s interaction with CCL21 promotes metastasis of cancer via lymph node. CCR7 is known to be associated with breast cancer, melanoma, colorectal cancer, non-small cell lung cancer, and chronic lymphocytic leukemia.

Características y beneficios

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Descripción de destino

Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.

Forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable