SAB2500042

Anti-AIF1/IBA1 (Isoform 3) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-AIF-1, Anti-Allograft inflammatory factor 1, Anti-DASS-82G15.2, Anti-IBA1, Anti-IRT-1
• Número MDL: MFCD02685938
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: goat
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• reactividad de especies: mouse, rat, human
• técnicas: immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• Nº de acceso UniProt: P55008
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... AIF1(199)

Descripción

Descripción general

AIF1 (allograft inflammatory factor 1) is a calcium-binding, cytoplasmic protein that has 143-amino acids. It is also known as IBA1 (ionized calcium-binding adapter molecule 1). It is expressed in the cells of the monocyte/macrophage lineage, as well as in microglial and dendritic cells. It is located on human chromosome 6p21.3.

Inmunógeno

Peptide with sequence C-NKQFLDDPKYSSDED from the internal region of the protein sequence according to NP_001614.3.

Aplicación

Anti-AIF1/IBA1 (Isoform 3) antibody produced in goat has been used in western blotting and immunofluorescence.

Acciones bioquímicas o fisiológicas

AIF1 (allograft inflammatory factor 1) is an essential factor of macrophage chemotaxis. Expression of AIF1 regulates the proliferation of vascular smooth muscle cells by G-CSF (cytokine granulocyte-colony stimulating factor) autocrine expression.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable