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Merck
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Key Documents

SAB1307254

Sigma-Aldrich

ANTI-BAT1(C-TERMINAL) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Sinónimos:

56 kDa U2AF65-associated protein, BAT1, DDX39B, Spliceosome RNA helicase DDX39B, UAP56

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

100

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

formulario

buffered aqueous solution

mol peso

48991 Da

reactividad de especies

human

técnicas

flow cytometry: 1:10-1:50
immunohistochemistry: 1:10-1:50
western blot: 1:1000

Nº de acceso NCBI

NP_004631.1

Nº de acceso UniProt

Q13838

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... DDX39B(7919)

Categorías relacionadas

Descripción general

BAT1, also known as UAP56 or DExD-box helicase 39B (DDX39B), is encoded in the central region of the major histocompatibility complex (MHC) on the short arm of human chromosome 6p21.33. It is a member of DEAD box family of RNA-binding proteins and is characterized with the nine conserved motifs including ATPase and RNA helicase motifs.

Aplicación

ANTI-BAT1(C-TERMINAL) antibody produced in rabbit has been used in immunoprecipitation and western blotting.

Acciones bioquímicas o fisiológicas

BAT1/ UAP56 facilitates the binding of U2 small nuclear ribonucleoprotein (SnRP) to pre-mRNA. It also helps in the export of mRNA from the nucleus to the cytoplasm. Spliceosome RNA helicase BAT1 is implicated in adapting nucleic acid metabolism to cellular stress. BAT1 is implicated in the down-regulation of inflammation. The gene polymorphism might be associated with the development of allergic diseases such as bronchial asthma, allergic rhinitis, atopic dermatitis, food allergy, drug allergy and pollen allergy. Mutation in the gene may also lead to the development of urticaria and Quincke′s edema.

Forma física

Supplied in PBS with 0.09% (W/V) sodium azide

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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M B Freĭdin et al.
Molekuliarnaia biologiia, 45(3), 464-472 (2011-07-28)
Genome-wide association studies are currently considered as one of the most powerful tools to establishing the genetic basis of complex diseases. A number of such studies were carried out for allergic diseases; however, in Russian population this analysis has not
Influenza Virus mRNA Trafficking Through Host Nuclear Speckles.
Mor A, et al.
Nature microbiology, 2016 (2016)
Ke Zhang et al.
Science advances, 7(6) (2021-02-07)
The ongoing unprecedented severe acute respiratory syndrome caused by the SARS-CoV-2 outbreak worldwide has highlighted the need for understanding viral-host interactions involved in mechanisms of virulence. Here, we show that the virulence factor Nsp1 protein of SARS-CoV-2 interacts with the
Matthew Esparza et al.
PLoS pathogens, 16(4), e1008407-e1008407 (2020-04-03)
Influenza A viruses are human pathogens with limited therapeutic options. Therefore, it is crucial to devise strategies for the identification of new classes of antiviral medications. The influenza A virus genome is constituted of 8 RNA segments. Two of these
Amir Mor et al.
Nature microbiology, 1(7), 16069-16069 (2016-08-31)
Influenza A virus is a human pathogen with a genome composed of eight viral RNA segments that replicate in the nucleus. Two viral mRNAs are alternatively spliced. The unspliced M1 mRNA is translated into the matrix M1 protein, while the

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