SAB1300666

Anti-SULT1B1 (C-term) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Sinónimos: Anti-1B, Anti-Cytosolic, Anti-Member 1, Anti-Sulfotransferase family, Sulfotransferase 1B2
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: IgG fraction of antiserum
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• reactividad de especies: human
• técnicas: indirect ELISA: 1:1000; western blot: 1:100-1:500
• Nº de acceso NCBI: NP_055280
• Nº de acceso UniProt: O43704
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... SULT1B1(27284)

Descripción

Descripción general

Sulfotransferases such as SULT1B1 catalyze the biotransformation of a large number of endogenous compounds such as neurotransmitters, steroids, bile acids, and thyroid hormones, as well as drugs and xenobiotics. Fujita et al. (1997) demonstrated that recombinant rat and human SULT1B1, expressed in E. coli, catalyzed sulfation of p-nitrophenol, 3,3-prime,5-triiodothyronine (T3), and dopamine, but not of beta-estradiol and dehydroepiandrosterone. SULT1B1 showed higher affinities for formation of T3 sulfate than did the phenol sulfotransferases ST1A3 (SULT1A1) or ST1A5. Wang et al. (1998) found that bacterially-expressed SULT1B1 sulfated small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3-prime-diiodothyronine, triiodothyronine, reverse triiodothyronine, and thyroxine. No activity was detected against several sterols or dopamine.

Inmunógeno

SULT1B1 (NP_055280, 268-306)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SULT1B1.

Forma física

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable