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Merck
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Key Documents

RAB0308

Sigma-Aldrich

Mouse IL-6 ELISA Kit

for serum, plasma and cell culture supernatant

Sinónimos:

B-cell stimulatory factor 2, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, IL-6, Interferon beta-2

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About This Item

Código UNSPSC:
41116158
NACRES:
NA.84

reactividad de especies

mouse

envase

kit of 96 wells (12 strips x 8 wells)

técnicas

ELISA: suitable
capture ELISA: suitable

entrada

sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2 pg/mL
standard curve range: 0.82-600 pg/mL

método de detección

colorimetric

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

Información sobre el gen

mouse ... Il6(24498)

Categorías relacionadas

Descripción general

The Mouse IL-6 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Mouse IL-6 in serum, plasma, cell culture supernatants and urine.

Inmunógeno

Recombinant Mouse IL-6

Aplicación

For research use only. Not for use in diagnostic procedures.
Mouse IL-6 ELISA kit has been used for determining the levels of IL-6 in biological samples.

Acciones bioquímicas o fisiológicas

IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism.

Otras notas

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Los componentes del kit también están disponibles por separado

Referencia del producto
Descripción
SDS
  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

Pictogramas

Corrosion
GHS05

Palabra de señalización

Warning

Frases de peligro

H290

Consejos de prudencia

P234 - P390

Clasificaciones de peligro

Met. Corr. 1

Código de clase de almacenamiento

8A - Combustible corrosive hazardous materials

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Journal of biological engineering, 16(1), 5-5 (2022-03-05)
Tenocytes as specialised fibroblasts and inherent cells of tendons require mechanical load for their homeostasis. However, how mechanical overload compared to physiological load impacts on the tenogenic differentiation potential of fibroblasts is largely unknown. Three-dimensional bioartificial tendons (BATs) seeded with
Willem T Peppler et al.
American journal of physiology. Gastrointestinal and liver physiology, 316(1), G166-G178 (2018-11-02)
Obesity can lead to impairments in hepatic glucose and insulin homeostasis, and although exercise is an effective treatment, the molecular targets remain incompletely understood. As IL-6 is an exercise-inducible cytokine, we aimed to identify whether IL-6 itself influences hepatic glucose
The biology of interleukin-6.
Kishimoto T
Blood, 74(1), 1-10 (1989)
Effect of HI-6 on cytokines production after immunity stimulation by keyhole limpet hemocyanin in a mouse model.
Pohanka M
Neuro Endocrinology Letters, 35, 155-157 (2014)
Ashley J Smuder et al.
Oncotarget, 11(38), 3502-3514 (2020-10-06)
Cancer cachexia is a syndrome characterized by profound cardiac and diaphragm muscle wasting, which increase the risk of morbidity in cancer patients due to failure of the cardiorespiratory system. In this regard, muscle relies greatly on mitochondria to meet energy
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