PRS4887

Anti-IL-17 (ab2) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-CTLA8, Anti-Interleukin 17A
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• reactividad de especies: human, mouse
• técnicas: immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• Nº de acceso UniProt: Q16552
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... IL17A(3605)

Descripción

Descripción general

IL-17A (interleukin 17A) is a proinflammatory cytokine of Th17 (helper T cells). It is located on chromosome 6p12.

Inmunógeno

a 19 amino acid peptide from near the center of human IL-17A.

Acciones bioquímicas o fisiológicas

IL-17A (interleukin 17A) plays a major role in the pathogenesis of autoimmune diseases like multiple sclerosis and rheumatoid arthritis. It also plays a pathogenic role in allergic rhinitis (AR). It helps in the formation of several chemokines and cytokines in airway epithelial cells.

Ligadura / enlace

The action of this antibody can be blocked using blocking peptide SBP4887.

Forma física

Solution in phosphate buffered saline containing 0.02% sodium azide

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable