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P5687

Sigma-Aldrich

Monoclonal Anti-Prostatic Acid Phosphatase, Human antibody produced in mouse

clone PAP-12, ascites fluid

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About This Item

Número MDL:
MFCD00163953
Código UNSPSC:
12352203
NACRES:
NA.46

origen biológico

mouse

Nivel de calidad

200

conjugado

unconjugated

forma del anticuerpo

ascites fluid

tipo de anticuerpo

primary antibodies

clon

PAP-12, monoclonal

contiene

15 mM sodium azide

reactividad de especies

human

técnicas

indirect ELISA: 1:800 using purified preparation of human prostatic acid phosphatase

isotipo

IgG1

Nº de acceso UniProt

P15309

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... ACPP(55)

Descripción general

The antibodies localize the 48 kDa subunit of prostatic acid phosphatase in immunoblotting, using reducing and denaturing conditions, without cross-reactivity to prostate specific antigen or other human serum or tissue proteins.

Inmunógeno

human prostatic acid phosphatase

Acciones bioquímicas o fisiológicas

Prostatic acid phosphatase (PAP) is a non-specific phosphomonoesterase synthesized in prostate epithelial cells. The major function of PAP is the regulation of prostate cell growth. The levels of PAP serve as marker for prostate cancer progression. PAP has been reported to exhibit antinociceptive effect in neuropathic and inflammatory pain that is characteristic of cancer-induced bone pain.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

nwg

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

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Lei Chen et al.
Pain physician, 16(6), 533-546 (2013-11-29)
Cancer-induced bone pain (CIBP) is a severe chronic pain that is less than adequately controlled by conventional analgesics. Prostatic acid phosphatase (PAP) has been considered as a diagnostic marker for prostate cancer and its transmembrane isoform has been reported to
Hoon Young Kong et al.
Biomolecules & therapeutics, 21(1), 10-20 (2013-09-07)
Prostate cancer is one of the most prevalent non-skin related cancers. It is the second leading cause of cancer deaths among males in most Western countries. If prostate cancer is diagnosed in its early stages, there is a higher probability
Paulo R Bueno et al.
Nanoscale, 9(40), 15362-15370 (2017-10-04)
The application of nanoscale capacitance as a transduction of molecular recognition relevant to molecular diagnostics is demonstrated. The energy-related signal relates directly to the electron occupation of quantized states present in readily fabricated molecular junctions such as those presented by

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