M6760

Myricetin

≥96.0%, crystalline

• Sinónimos: 3,3′,4′,5,5′,7-Hexahydroxyflavone, Cannabiscetin, Myricetol
• Fórmula empírica (notación de Hill): C₁₅H₁₀O₈
• Número de CAS: 529-44-2
• Peso molecular: 318.24
• Beilstein: 332331
• Número CE: 208-463-2
• Número MDL: MFCD00006827
• Código UNSPSC: 12352202
• ID de la sustancia en PubChem: 24278566
• NACRES: NA.77

Propiedades

• Ensayo: ≥96.0%
• Formulario: crystalline
• mp: >300 °C (lit.)
• solubilidad: absolute ethanol: 10 mg/mL, clear to slightly hazy, yellow to very deep greenish-yellow
• cadena SMILES: Oc1cc(O)c2C(=O)C(O)=C(Oc2c1)c3cc(O)c(O)c(O)c3
• InChI: 1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H
• Clave InChI: IKMDFBPHZNJCSN-UHFFFAOYSA-N
• Información sobre el gen: human ... CYP1A2(1544) ; mouse ... Hexa(15211) ; rat ... Il4(287287) , Tnf(24835)

Descripción

Aplicación

Myricetin has been used:

• to investigate its effect on end product (AGE)- bovine serum albumin mediated phosphorylation of mitogen-activated protein kinase(ERK1)
• as a standard for the quantification of phenolics from noni plant extracts using high performance liquid chromatography(HPLC)
• as a standard for characterization of phenolic compounds from Hibiscus sabdariffa using ultra-high performance liquid chromatography(UHPLC)

Acciones bioquímicas o fisiológicas

Myricetin is a naturally occurring flavonol with antioxidant property. It displays moderate membrane permeability and it degrades rapidly at elevated pH. Myricetin is one of the major flavonoid present in edible plants and has anticarcinogenic and antimutagenic functionality. It comprises of two benzene rings A and B. Ring B intercalates with nucleotide staking and inhibits bacterial DNA synthesis. Myricetin elicits protective function against oxidative stress generated by tert-butylhydroperoxide (t-BHP) in diabetic rat and improves glutathione peroxidase (GPx) and xanthine oxidase (XO) enzyme activity. It also lowers the glycation of low-density lipoprotein.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)