L4516
Lipopolysaccharides from Escherichia coli O127:B8
BioXtra, suitable for cell culture, γ-irradiated
Sinónimos:
LPS
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About This Item
origen biológico
Escherichia coli (O127:B8)
Nivel de calidad
esterilidad
γ-irradiated
Línea del producto
BioXtra
formulario
lyophilized powder
purificado por
gel-filtration chromatography
técnicas
cell culture | mammalian: suitable
impurezas
<1% Protein (Lowry)
solubilidad
H2O: 5 mg/mL, slightly hazy
temp. de almacenamiento
2-8°C
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Aplicación
Lipopolysaccharides from Escherichia coli 0127:B8 has been used:
- to study the LPS-induced macrophage survival in mice
- to elicit the secretion of cytokines by cattle PBMC
- to study apoptosis of highly susceptible macrophage cells in a LPS-induced proinflammatory environment
- to perform autophagy assay in BV2 and BV2-LC3 cells
- for stimulation of human monocytes, macrophages and mouse microglia cells
- to induce pentraxin-3 expression in 293T cells
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).
Acciones bioquímicas o fisiológicas
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4). Being an immunogenic antigen, it enhances immune responses to soluble antigens.
Reconstitución
Lipopolysaccharides are supplied as lyophilized, γ-irradiated powders. To reconstitute, add 1 ml sterile balanced salt solution or tissue culture medium to the vial (1 mg) and gently swirl until the powder dissolves. Reconstituted product may be further diluted to desired working concentrations using sterile balanced salt solution or tissue culture medium.
Otras notas
To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Producto relacionado
Referencia del producto
Descripción
Precios
Palabra de señalización
Danger
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Acute Tox. 2 Oral
Código de clase de almacenamiento
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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