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Key Documents

L2143

Sigma-Aldrich

Lipopolysaccharides from Escherichia coli K-235

purified by phenol extraction

Sinónimos:

LPS

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About This Item

Número CE:
Número MDL:
Código UNSPSC:
12352201
NACRES:
NA.25

origen biológico

Escherichia coli (K-235)

Nivel de calidad

formulario

lyophilized powder

purificado por

phenol extraction

impurezas

<3% Protein (Lowry)

color

white to faint yellow

solubilidad

water: soluble

Condiciones de envío

ambient

temp. de almacenamiento

2-8°C

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Descripción general

This product is phenol extracted from E. coli serotype K235. The source strain is ATCC 13027.

Aplicación


  • Establishment of disseminated intravascular coagulation (DIC) model by a single iv administration of Escherichia coli-derived lipopolysaccharide (LPS) to cynomolgus monkeys and evaluation of its pathophysiological status.: This study established a DIC model in cynomolgus monkeys using E. coli-derived LPS, providing insights into the pathophysiological status and potential therapeutic interventions for DIC (Minomo et al., 2017).

  • Different bacterial lipopolysaccharides as toxicants and stressors in the shrimp Palaemon elegans.: This research explored the toxic effects of various bacterial LPS, including E. coli K-235, on the shrimp Palaemon elegans, advancing the understanding of LPS-induced stress responses in marine organisms (Lorenzon et al., 2002).

Acciones bioquímicas o fisiológicas

Lipopolysaccharides (LPS) are localized in the outer layer of the membrane and are, in noncapsulated strains, exposed on the cell surface. They contribute to the integrity of the outer membrane, and protect the cell against the action of bile salts and lipophilic antibiotics.

Nota de preparación

The product is soluble in water (5 mg/ml) or cell culture medium (1 mg/ml) yielding a hazy, faint yellow solution. A more concentrated, though still hazy, solution (20 mg/ml) has been achieved in aqueous saline after vortexing and warming to 70-80 oC. Lipopolysaccharides are molecules that form micelles in every solvent. Hazy solutions are observed in water and phosphate buffered saline. Organic solvents do not give clearer solutions. Methanol yields a turbid suspension with floaters, while water yields a homogeneously hazy solution.

Otras notas

To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Producto relacionado

Referencia del producto
Descripción
Precios

Pictogramas

Skull and crossbones

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Acute Tox. 2 Oral

Código de clase de almacenamiento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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