H8909
HBcAg core human
~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed in E. coli
Sinónimos:
Hepatitis B virus core antigen
Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
About This Item
Productos recomendados
recombinante
expressed in E. coli
Nivel de calidad
Análisis
≥95% (SDS-PAGE)
mol peso
18 kDa
concentración
~1 mg/mL
Nº de acceso UniProt
temp. de almacenamiento
−20°C
Información sobre el gen
hepatitis B virus ... HBVgp4(944568)
human ... HBVgp4(944568)
Descripción general
amino acids 1-183 of HBV core antigen.
Acciones bioquímicas o fisiológicas
HBcAg core human is a capsid protein of hepatitis B virus (HBV). It acts as a viral factor for HBV clearance. HBcAg is implicated in viral replication.
Hepatitis B virus core antigen (HBcAg) is a positive control for human HBV antibodies.In humans with chronic HBV (hepatitis B virus) infection, cytotoxic effects of blood T lymphocytes can be suppressed by incubating cells with antibodies against hepatitis B core antigen (HBcAg). The antigen can also work as a T-cell independent antigen in athymic mice. However, it is an efficient immunogen, resulting in T-cell activation and increased anti-HBc levels. High cytoplasmic/membranous expression of HBcAg is associated with increased liver inflammation.
Forma física
Solution in 50% glycerol, 7.5 mM phosphate buffer, pH 7.2, 75 mM NaCl.
Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 1
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
M Mondelli et al.
Journal of immunology (Baltimore, Md. : 1950), 129(6), 2773-2778 (1982-12-01)
Peripheral blood T lymphocytes from 21 patients with chronic HBV infection were incubated with autologous hepatocytes in a microcytotoxicity assay. Cytotoxicity was significantly increased in 13 cases, and in 12 of these the cytotoxic effect of the T lymphocytes was
C M Chu et al.
Gastroenterology, 92(1), 220-225 (1987-01-01)
The intrahepatic distribution of hepatitis B core antigen (HBcAg) and surface antigen (HBsAg) was studied in 32 patients with chronic type B hepatitis, and the results were correlated with the status of hepatitis B e antigen/antibody (HBeAg/anti-HBe) and with the
D R Milich et al.
Journal of immunology (Baltimore, Md. : 1950), 139(4), 1223-1231 (1987-08-15)
Hepatitis B virus nucleocapsid particles (HBcAg) can function as a T cell-independent antigen when injected into athymic mice. However, immunization of euthymic mice with HBcAg results in dramatically increased anti-HBc titers. Therefore we have examined the murine T cell response
Jun Hong et al.
Hepatology research : the official journal of the Japan Society of Hepatology, 38(4), 362-373 (2007-11-21)
This study was undertaken to investigate whether plasmacytoid dendritic cells (PDC) are involved in the generation of a higher proportion of CD4(+) and CD25(+) regulatory T (Treg) cells in chronic hepatitis B virus (HBV) infection compared with healthy patients. The
Hepatitis B virus nucleocapsid but not free core antigen controls viral clearance in mice
Lin YJ, et al.
Journal of Virology, 86(17), 9266-9273 (2012)
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico