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Merck
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H3791

Sigma-Aldrich

Anti-HOXA3 antibody produced in rabbit

~1.0 mL/mL, affinity isolated antibody

Sinónimos:

Anti-HOX1, Anti-HOX1E, Anti-Homeobox A3, Anti-MGC10155

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About This Item

Número MDL:
MFCD02263083
Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

formulario

buffered aqueous solution

mol peso

antigen ~60 kDa

reactividad de especies

human, mouse

envase

antibody small pack of 25 μL

concentración

~1.0 mL/mL

técnicas

immunoprecipitation (IP): 5-10 μg using lysates of HEK-293T cells expressing human HOXA3
indirect immunofluorescence: 2-5 μg/mL using paraformaldehyde fixed HEK-293T cells over expressing human HOXA3
western blot: 2-4 μg/mL using lysates of HEK-293T cells over expressing human HOXA3

Nº de acceso UniProt

O43365

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... HOXA3(3200)
mouse ... Hoxa3(15400)

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Descripción general

Homeobox A3 (HOXA3) transcription factor/protein belongs to the HOX family. The HOXA3 gene is mapped on the human chromosome at 7p15.2.

Especificidad

Anti-HOXA3 specifically recognizes HOXA3.

Aplicación

Anti-HOXA3 antibody produced in rabbit may be used in:
  • proximity ligation assay
  • immunoblotting
  • immunoprecipitation
  • immunofluorescence

Acciones bioquímicas o fisiológicas

Disruption of the homeobox A3 (HOXA3) gene results in embryonic lethality, which was rescued by placing HOXD3. HOXA3 gene expression is upregulated during neovascularization as a result of injury indicating that HOXA3 promotes angiogenesis. Mutations of the HOXA3 gene are associated with defects in thymus organogenesis and parathyroid development.

Forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Almacenamiento y estabilidad

Store at −20 °C. For continuous use, store at 2–8 °C for up to one month. For extended storage, freeze at −20 °C in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation. Discard working dilutions if not used within 12 hours.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

nwg

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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D Su et al.
Developmental biology, 236(2), 316-329 (2001-07-31)
The thymus and parathyroid glands in mice develop from a thymus/parathyroid primordium that forms from the endoderm of the third pharyngeal pouch. We investigated the molecular mechanisms that promote this unique process in which two distinct organs form from a
Maria Fernanda Setúbal Destro Rodrigues et al.
Genomics, 108(5-6), 185-193 (2016-11-09)
Approximately 300 homeobox loci were identified in the euchromatic regions of the human genome, of which 235 are probable functional genes and 65 are likely pseudogenes. Many of these genes play important roles in embryonic development and cell differentiation. Dysregulation

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