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GERPN6301

Thiourea

Cytiva RPN6301, pack of 100 g

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About This Item

Código UNSPSC:
41105323
NACRES:
NA.77

Formulario

solid

Características

wetted part: no

envase

pack of 100 g

fabricante / nombre comercial

Cytiva RPN6301

color

White

intervalo de pH

5-7

solubilidad

cold water: soluble (Soluble in cold water and hot water)
diethyl ether: soluble (Partially soluble in diethyl ether)
methanol: soluble (Easily soluble in methanol)

Descripción general

Thiourea is a chaotrope used together with urea in the IPG strip rehydration to solubilize and denature proteins, and improve the solubility of membrane proteins.

Aplicación

Thiourea has been used as a component of lysis buffer for solubilization of the proteins from tissue samples and T-leukemia cells. It has also been used as a component of sample buffer for placental tissue, leaf proteome, and 2D electrophoresis.

Acciones bioquímicas o fisiológicas

Thiourea is an organic compound and its derivatives have antibacterial, antiviral, antifungal and insecticidal property. It is actively used in the drug development against human immunodeficiency virus (HIV) and hepatitis C infection. Thiourea inhibits cyclooxygenase enzyme and effectively reduces prostaglandin E2 (PGE2) and thromboxane (TXB2) production and is antithrombotic in human platelets. It is cytotoxic to vaginal epithelial cells and may function as potent spermicidal agent. Thiourea based derivatives of anticancer drug sorafenib, eliclits antiproliferative activity in human colon cancer cell line, HCT116 cells.

Almacenamiento y estabilidad

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.

Nota de análisis

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Pictogramas

Environment
GHS09

Palabra de señalización

Warning

Frases de peligro

H302,H361d,H351,H411

Código de clase de almacenamiento

13 - Non Combustible Solids

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Certificados de análisis (COA)

Lot/Batch Number

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SDS Cytiva 17-1313-01, pack of 100 g

GE17-1313-01

SDS

DL-Ditiotreitol suitable for electrophoresis, ≥99%

Sigma-Aldrich

D9163

DL-Ditiotreitol

N- Metil-D-glucamina 99.0-100.5% (titration)

Sigma-Aldrich

M2004

N- Metil-D-glucamina

Yodoacetamida BioUltra

Sigma-Aldrich

I1149

Yodoacetamida

Urea powder, BioReagent, for molecular biology, suitable for cell culture

Sigma-Aldrich

U5378

Urea

Novel thiourea compounds as dual-function microbicides
D?Cruz, OJ, et al.
Biology of Reproduction, 63(1), 196-205 (2000)
Synthesis and antiplatelet activity of antithrombotic thiourea compounds: biological and structure-activity relationship studies
Lourencco A, et al.
Molecules (Basel), 20(4), 7174-7200 (2015)
Synthesis, Characterization, Biological Activity and Use of Thiourea Derivative (PhTTU) Studies of dinitrate-1-phenyl-3-(thiazol-2-yl)-2-thioureato Cd (II) ion Complex
Alfallous KA and Aburzeza MM
International Journal of Scientific Research, 4(6) (2015)
Capabilities using 2-D DIGE in proteomics research
Tissue proteomics, 1-18 (2008)
Spontaneous Unexplained Preterm Labor with Intact Membrane: Finding Protein Biomarkers through Placenta Proteome
Electrophoresis-Life Sciences Practical Applications (2018)
Ver todos los artículos relacionados

Artículos

Components of Rehydration Solution

This page describes components of rehydration solutions for use in 2-D Electrophoresis with GE Healthcare products.

Protocolos

Rehydration Solutions

Rehydration Solutions

Two-Dimensional Separation of Protein Samples

This page describes two-dimensional separation of protein samples with GE Healthcare products.

Global Trade Item Number

Número de referencia del producto (SKU)GTIN
GERPN63014061834085348

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

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