G7403

Glicina

≥99% (titration), suitable for electron microscopy, BioXtra

• Sinónimos: Glicocola, Ácido aminoacético, Ácido aminoetanoico
• Fórmula lineal: NH₂CH₂COOH
• Número de CAS: 56-40-6
• Peso molecular: 75.07
• Beilstein: 635782
• Número CE: 200-272-2
• Número MDL: MFCD00008131
• Código UNSPSC: 12352209
• eCl@ss: 32160406
• ID de la sustancia en PubChem: 24895306
• NACRES: NA.26

Propiedades

• product name: Glicina, BioXtra, ≥99% (titration)
• Línea del producto: BioXtra
• Nivel de calidad: 200
• Análisis: ≥99% (titration)
• formulario: powder
• técnicas: electron microscopy: suitable
• impurezas: Insoluble matter, passes filter test
• residuo de ign.: ≤0.05%
• pérdida: ≤0.05% loss on drying, HV, 20-26 °C
• color: white
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• mp: 240 °C (dec.) (lit.)
• solubilidad: 1 M HCl: 1 M, clear, colorless
• trazas de anión: chloride (Cl^-): ≤0.005%; sulfate (SO₄^2-): ≤0.005%
• trazas de catión: Al: ≤0.0005%; As: ≤0.00001%; Ba: ≤0.0005%; Bi: ≤0.0005%; Ca: ≤0.001%; Cd: ≤0.0005%; Co: ≤0.0005%; Cr: ≤0.0005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.005%; Li: ≤0.0005%; Mg: ≤0.0005%; Mn: ≤0.0005%; Mo: ≤0.0005%; NH₄⁺: ≤0.02%; Na: ≤0.02%; Ni: ≤0.0005%; Pb: ≤0.0005%; Sr: ≤0.0005%; Zn: ≤0.0005%
• absorción: ≤0.04 at 260 in 1 M HCl at 1 M; ≤0.04 at 280 in 1 M HCl at 1 M
• cadena SMILES: NCC(O)=O
• Absorción UV: λ: 260 nm A_max: ≤0.04; λ: 260 nm A_max: 0.003; λ: 260 nm A_max: 0.006
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• Clave InChI: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Información sobre el gen: rat ... Grin2a(24409)

Descripción

Aplicación

Glycine has been used to quench unreacted aldehyde during sample (nuclei) preparation for scanning electron microscope. It has also been used for sample fixation in the process of immunolabeling.

Acciones bioquímicas o fisiológicas

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Neurotransmisor inhibidor de la médula espinal, regulador alostérico de los receptores NMDA.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)