G5422
β-Glycerophosphate disodium salt hydrate
≤1.0 mol % L-α-isomer
Sinónimos:
BGP, Glycerol 2-phosphate disodium salt hydrate
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About This Item
Fórmula lineal:
(HOCH2)2CHOP(O)(ONa)2 · xH2O
Número de CAS:
Peso molecular:
216.04 (anhydrous basis)
Número CE:
Número MDL:
Código UNSPSC:
12352201
ID de la sustancia en PubChem:
NACRES:
NA.25
Productos recomendados
origen biológico
synthetic
Nivel de calidad
Formulario
powder
impurezas
≤0.1% Inorganic phosphorus
≤1.0 mol % L-α-isomer
mp
102-104 °C (lit.)
solubilidad
water: 50 mg/mL, clear, colorless
cadena SMILES
O.[Na+].[Na+].OCC(CO)OP([O-])([O-])=O
InChI
1S/C3H9O6P.2Na.H2O/c4-1-3(2-5)9-10(6,7)8;;;/h3-5H,1-2H2,(H2,6,7,8);;;1H2/q;2*+1;/p-2
Clave InChI
ROPZSVKNEIIIDE-UHFFFAOYSA-L
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Aplicación
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It functions as an organic phosphate donor and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells. BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression.
β-glycerophosphate is used in homegenization solutions for muscles extracts following fixation.
Initiates differentiation of bone-marrow-derived stem cells embedded in a natural collagen/chitosan gel designed for tissue engineering.
Calidad
Low inorganic phosphate content. Mixtures of α- and β-glycerophosphate have historically been used in microbiological media but high levels of inorganic (free) phosphate has been associated with the irregular growth of bacteria and unwanted precipitates.
Palabra de señalización
Warning
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Eye Irrit. 2
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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The aim of this study was to evaluate the effect of strontium ranelate (SrR) on bone mineral density (BMD) and bone turnover markers after 1 year of treatment. Additionally, the effect of SrR in bisphosphonate-naïve patients (BP-naïve) compared to patients previously
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