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G5131

Sigma-Aldrich

Guanosine 5′-diphospho-D-mannose sodium salt from Saccharomyces cerevisiae

Type I, ≥97% (HPLC)

Sinónimos:

GDP-Man, GDP-mannose

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About This Item

Fórmula lineal:
C16H23N5O16P2Na2
Número de CAS:
103301-73-1
Peso molecular:
649.30
Número MDL:
MFCD00070120
Código UNSPSC:
41106305
ID de la sustancia en PubChem:
24895196
NACRES:
NA.51

tpo

Type I

Análisis

≥97% (HPLC)

temp. de almacenamiento

−20°C

cadena SMILES

[Na].NC1=NC(=O)c2ncn(C3OC(COP(O)(=O)OP(O)(=O)OC4OC(CO)C(O)C(O)C4O)C(O)C3O)c2N1

InChI

1S/C16H25N5O16P2.Na.H/c17-16-19-12-6(13(28)20-16)18-3-21(12)14-10(26)8(24)5(34-14)2-33-38(29,30)37-39(31,32)36-15-11(27)9(25)7(23)4(1-22)35-15;;/h3-5,7-11,14-15,22-27H,1-2H2,(H,29,30)(H,31,32)(H3,17,19,20,28);;

Clave InChI

MEXITZOHWLXZKR-UHFFFAOYSA-N

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Descripción general

Guanosine 5′-diphospho-D-mannose (GDP-D-mannose) is present in high cytosolic levels in Saccharomyces cerevisiae. It is crucial for protein mannosylation. GDP-D-mannose is an important precursor to produce GDP-l-fucose.

Aplicación

Guanosine 5′-diphospho-D-mannose sodium salt from Saccharomyces cerevisiae has been used as a nucleotide sugar in transglycosylation enzymatic assay and hydrolysis based catalytic reactions with S-glycosyltransferases (SunS).
Guanosine 5′-diphospho-D-mannose sodium salt has been used as a component of ATP regeneration system for in vitro vesicle formation from Saccharomyces cerevisiae microsomes. It has also been used as a component of the buffer for mannosyl transferase activity assay.

Acciones bioquímicas o fisiológicas

Guanosine diphosphate mannose (GDP-mannose) is a nucleotide sugar substrate for glycosyltransferase (mannosylation) reactions mediated by mannosyltransferases.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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The coronary club.
M M Gilliland
Supervisor nurse, 10(3), 50-51 (1979-03-01)
Daniel C Turnock et al.
Eukaryotic cell, 6(8), 1450-1463 (2007-06-15)
The cell surface glycoconjugates of trypanosomatid parasites are intimately involved in parasite survival, infectivity, and virulence in their insect vectors and mammalian hosts. Although there is a considerable body of work describing their structure, biosynthesis, and function, little is known
N Smirnoff
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 355(1402), 1455-1464 (2000-12-29)
Ascorbate (vitamin C) can reach very high concentrations in chloroplasts (20-300 mM). The pool size in leaves and chloroplasts increases during acclimation to high light intensity and the highest concentrations recorded are in high alpine plants. Multiple functions for ascorbate
Lysophospholipids facilitate COPII vesicle formation
Melero A, et al.
Current Biology, 28(12), 1950-1958 (2018)
Two KTR Mannosyltransferases Are Responsible for the Biosynthesis of Cell Wall Mannans and Control Polarized Growth in Aspergillus fumigatus
Henry C, et al.
mBio, 10(1), e02647-e02618 (2019)
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