F9911

Fibronectin Proteolytic Fragment from human plasma

lyophilized powder, 30 kDa

• Código UNSPSC: 12352202
• eCl@ss: 42020141
• NACRES: NA.75

Propiedades

• origen biológico: human plasma
• Nivel de calidad: 200
• Análisis: >90% (SDS-PAGE)
• formulario: lyophilized powder
• mol peso: 30 kDa
• envase: pkg of 0.5 mg
• técnicas: cell culture | mammalian: suitable
• impurezas: HIV and HBsAg, source material tested negative; Small proteolytic fragments, may contain traces
• solubilidad: water: soluble >0.5 mg/mL, clear to slightly hazy, colorless
• Nº de acceso UniProt: P02751
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... FN1(2335)

Descripción

Descripción general

Fibronectin 1 is a glycoprotein of the extracellular matrix that is coded by FN1 gene. It is expressed in the plasma and at the cell surface. FN1 is mapped to human chromosome 2q35. Proteolytic fragments of fibronectin has a cell binding domain.

Aplicación

Fibronectin proteolytic fragment has been used in solid phase binding assay.

Acciones bioquímicas o fisiológicas

Fibronectin participates in cell adhesion, growth, migration, wound healing, blood coagulation and metastasis. Mutations in FN1 results in glomerulopathy. It plays an important role in cell attachment and spreading, control of cell cytoskeleton, morphology and differentiation. FN1 is also involved in extracellular matrix formation, hemostasis and thrombosis. Proteolytic fragments of fibronectin plays a vital role in mononuclear phagocyte function.

Precaución

The product should be stored at -20°C.

Nota de preparación

This product is lyophilized from phosphate buffered saline with sucrose as a cryoprotectant. The source material has tested negative for antibody to HIV, HCN, and HBsAg. It is soluble in water at 0.5 mg/mL and yields a clear to slightly hazy solution.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H315,H319,H335
• Consejos de prudencia: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Clasificaciones de peligro: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órganos de actuación: Respiratory system
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable