F5178

Flavin-Containing Monooxygenase-5, Microsomes human

recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)

• Sinónimos: FMO-5
• Comisión internacional de enzimas: 1.14.13.8 (BRENDA, IUBMB)
• Código UNSPSC: 12352204
• NACRES: NA.54

Propiedades

• recombinante: expressed in baculovirus infected insect cells
• Nivel de calidad: 200
• Formulario: buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)
• actividad específica: ≥700 units/mg protein
• mol peso: 55-60 kDa
• envase: vial of 2.5 mg
• Nº de acceso UniProt: P49326
• Condiciones de envío: dry ice
• temp. de almacenamiento: −70°C
• Información sobre el gen: human ... FMO5(2330)

Descripción

Aplicación

FMO5 is the only FMO isoform expressed in both adult and fetal human liver.

Acciones bioquímicas o fisiológicas

FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens, which demonstrate a nucleophilic nitrogen, sulfur, selenium, and phosphorous-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes. FMO5 is the only FMO isoform expressed in both adult and fetal human liver.

Definición de unidad

methyl p-tolyl sulfide oxidase activity: One unit will catalyze the production of 1.0 picomole of methyl p-tolyl sulfoxide.

Forma física

Solution in 100 mM potassium phosphate buffer, pH 7.4.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)