F1678

R-(−)-Fluoxetine hydrochloride

>98% (HPLC), solid

• Sinónimos: (R)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine hydrochloride
• Fórmula empírica (notación de Hill): C₁₇H₁₈NOF₃ · HCl
• Número de CAS: 114247-09-5
• Peso molecular: 345.79
• Número MDL: MFCD04040065
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 24278433
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Ensayo: >98% (HPLC)
• Formulario: solid
• condiciones de almacenamiento: desiccated
• color: white
• solubilidad: H₂O: soluble >10 mg/mL
• emisor: Eli Lilly
• cadena SMILES: Cl[H].CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c2ccccc2
• InChI: 1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m1./s1
• Clave InChI: GIYXAJPCNFJEHY-PKLMIRHRSA-N
• Información sobre el gen: human ... HTR1A(3350) , HTR1B(3351) , HTR1D(3352) , HTR1E(3354) , HTR1F(3355) , HTR2A(3356) , HTR2B(3357) , HTR2C(3358) , HTR3A(3359) , HTR3B(9177) , HTR3C(170572) , HTR3D(200909) , HTR3E(285242) , HTR4(3360) , HTR5A(3361) , HTR5B(645694) , HTR6(3362) , HTR7(3363)

Descripción

Aplicación

R-(−)-Fluoxetine hydrochloride has been used as a serotonin reuptake inhibitor:

• to study its effects on the embryoid body (EB) morphogenesis
• in combination with muscimol hydrobromide (MUS) as well as individually to study its neurotoxic effects on neuronal cells grown on multielectrode array (MEA) chips
• to study its effects as an endocrine disruption inducer in Pimephales promelas

Acciones bioquímicas o fisiológicas

Fluoxetine exhibits anti-depressant activity by increasing the serotonin levels in the neuron synaptic space. It also exhibits therapeutic effects against depression and other mood disorders.

Selective serotonin reuptake inhibitor.

Características y beneficios

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• Pictogramas: GHS05,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H302,H315,H318
• Consejos de prudencia: P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310
• Clasificaciones de peligro: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves