E6530

Etomidate

>98% (HPLC), powder

• Sinónimos: (R)-1-(α-Methylbenzyl)imidazole-5-carboxylic acid ethyl ester, Amidate, R16659
• Fórmula empírica (notación de Hill): C₁₄H₁₆N₂O₂
• Número de CAS: 33125-97-2
• Peso molecular: 244.29
• Número CE: 251-385-9
• Número MDL: MFCD00869295
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 24894630
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Ensayo: >98% (HPLC)
• Formulario: powder
• color: white
• solubilidad: DMSO: >10 mg/mL
• emisor: Johnson & Johnson
• temp. de almacenamiento: 2-8°C
• cadena SMILES: CCOC(=O)c1cncn1[C@H](C)c2ccccc2
• InChI: 1S/C14H16N2O2/c1-3-18-14(17)13-9-15-10-16(13)11(2)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3/t11-/m1/s1
• Clave InChI: NPUKDXXFDDZOKR-LLVKDONJSA-N
• Información sobre el gen: human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

Descripción

Descripción general

Etomidate is an imidazole derivative, which functions as an nonbarbiturate hypnotic agent. It is used in speech and memory test. Etomidate regulates hemodynamic stability by preserving sympathetic outflow and autonomic reflexes. It inhibits adrenal steroidogenesis.

Acciones bioquímicas o fisiológicas

Etomidate is a general anesthetic; potentiates GABA_A transmission

Etomidate is a general anesthetic; potentiates GABAA transmission. The possible neuroprotective effect of etomidate against streptozotocin-induced (STZ-induced) hyperglycaemia were investigated in the rat brain and spinal cord. Etomidate treatment demonstrated neuroprotective effect on the neuronal tissue against the diabetic oxidative damage

Características y beneficios

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• Pictogramas: GHS07,GHS09
• Palabra de señalización: Warning
• Frases de peligro: H302,H410
• Consejos de prudencia: P273 - P301 + P312 + P330
• Clasificaciones de peligro: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves