C4780

Coenzima A sodium salt hydrate

BioReagent, suitable for cell culture

• Sinónimos: CoA Na₂
• Fórmula empírica (notación de Hill): C₂₁H₃₆N₇O₁₆P₃S · xNa⁺ · yH₂O
• Número de CAS: 55672-92-9
• Peso molecular: 767.53 (anhydrous free acid basis)
• Número CE: 259-747-8
• Código UNSPSC: 12352205
• ID de la sustancia en PubChem: 24892723
• NACRES: NA.75

Propiedades

• origen biológico: yeast
• Nivel de calidad: 200
• descripción: cofactor for acyl transfer
• Línea del producto: BioReagent
• Análisis: ≥85% (HPLC)
• formulario: powder
• técnicas: cell culture | mammalian: suitable
• solubilidad: water: 50 mg/mL, clear, colorless to faintly yellow
• temp. de almacenamiento: −20°C
• cadena SMILES: [Na+].CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)([O-])=O)n2cnc3c(N)ncnc23)C(O)C(=O)NCCC(=O)NCCS
• Clave InChI: SYTRWOCXZXQBPW-CLVRNSBASA-M

Descripción

Aplicación

Coenzyme A sodium salt hydrate has been used:

• in the branch chain aminotransferase enzymatic assay and protein determination
• in the assay for halogenation of pyrrolyl-S-Bmp1 (an acyl carrier protein (ACP)-thioesterase (TE) di-domain protein) by Bmp2
• as an extracellular coenzyme A (CoA) in in vitro and in vivo experiments to study alternative routes by which cells and organisms can obtain CoA

Acciones bioquímicas o fisiológicas

Coenzyme A (CoA) is a ubiquitous cofactor that plays an important role in many metabolic pathways, mainly as acyl-CoA. It is essential for the tricarboxylic acid cycle, and the synthesis and oxidation of fatty acids. CoA facilitates acyl group transfers, especially in fatty acid and lipid metabolism reactions. It is associated with neurodegeneration, autophagy, protein acetylation, and signal transduction.

Calidad

Enzymatically assayed using phosphotransacetylase. Approx. 95% CoA-SH

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)