C4282

Coenzyme A hydrate

≥85% (UV, HPLC)

• Sinónimos: CoA
• Fórmula empírica (notación de Hill): C₂₁H₃₆N₇O₁₆P₃S · xH₂O
• Número de CAS: 85-61-0
• Peso molecular: 767.53 (anhydrous basis)
• Beilstein: 77809
• Número MDL: MFCD06795839
• Código UNSPSC: 12352100
• ID de la sustancia en PubChem: 24892684
• NACRES: NA.21

Propiedades

• origen biológico: yeast
• Nivel de calidad: 200
• Ensayo: ≥85% (UV, HPLC)
• Formulario: powder
• grupo funcional: phospholipid
• Condiciones de envío: ambient
• temp. de almacenamiento: −70°C
• cadena SMILES: O.CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n2cnc3c(N)ncnc23)[C@@H](O)C(=O)NCCC(=O)NCCS
• InChI: 1S/C21H36N7O16P3S.H2O/c1-21(2,16(31)19(32)24-4-3-12(29)23-5-6-48)8-41-47(38,39)44-46(36,37)40-7-11-15(43-45(33,34)35)14(30)20(42-11)28-10-27-13-17(22)25-9-26-18(13)28;/h9-11,14-16,20,30-31,48H,3-8H2,1-2H3,(H,23,29)(H,24,32)(H,36,37)(H,38,39)(H2,22,25,26)(H2,33,34,35);1H2/t11-,14-,15-,16+,20-;/m1./s1
• Clave InChI: TVSAELAFGDOPKI-BLPRJPCASA-N

Descripción

Aplicación

Coenzyme A hydrate has been used in the thiolase enzyme assay of recombinant acetoacetyl-CoA thiolase (rACAT) in Clonorchis sinensis. It may be used as a reference standard in Raman spectra measurements.

Acciones bioquímicas o fisiológicas

Coenzyme A (CoA) is an essential metabolic cofactor synthesized from cysteine, pantothenate, and ATP.

Coenzyme A (CoA) is an essential metabolic cofactor synthesized from cysteine, pantothenate, and ATP. CoA plays important roles in many metabolic pathways, including the tricarboxylic acid cycle, and the synthesis and oxidation of fatty acids. One of the main functions of CoA is the carrying and transfer of acyl groups. Acylated deriviates, for example acetyl-CoA, are critical intermediates in many metabolic reactions. CoA levels can be altered during starvation, and in conditions such as cancer, diabetes, and alcoholism.

Precaución

The free acid is less stable than the sodium or lithium salt; 5% decomposition may occur within 6 months when stored at −80 °C.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable