C4542

Cyclobenzaprine hydrochloride

• Sinónimos: 5-(3-Dimethylaminopropylidene)dibenzo[a,e]cycloheptatriene hydrochloride
• Fórmula empírica (notación de Hill): C₂₀H₂₁N · HCl
• Número de CAS: 6202-23-9
• Peso molecular: 311.85
• Número CE: 228-264-4
• Número MDL: MFCD00079039
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 24278315
• NACRES: NA.77

Propiedades

• Formulario: powder
• Nivel de calidad: 200
• emisor: Johnson & Johnson
• cadena SMILES: Cl.CN(C)CC\C=C1\c2ccccc2C=Cc3ccccc13
• InChI: 1S/C20H21N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-14H,7,15H2,1-2H3;1H
• Clave InChI: VXEAYBOGHINOKW-UHFFFAOYSA-N
• Información sobre el gen: human ... HTR2A(3356) , HTR2B(3357) , HTR2C(3358)

Descripción

Descripción general

Cyclobenzaprine is a tricyclic agent, which has anti-depressant and anti-cholinergic properties. It lowers the tonic somatic motor activity of motor neuron systems. Cyclobenzaprine prevents the uptake of noradrenaline. It is used to treat neck, back and myofascial pain. Cyclobenzaprine functions as a nerve impulse inhibitor.

Aplicación

Cyclobenzaprine hydrochloride has been used to study its effect on the muscles of dystrophin-deficient mdx5Cv mice.

Cyclobenzaprine hydrochloride has been used to study its effects on the muscles of dystrophin-deficient mdx5Cv mice.

Acciones bioquímicas o fisiológicas

Cyclobenzaprine hydrochloride is a type of tricyclic skeletal drug, which is commonly used as a muscle relaxant. It is very effective in treating intractable pain of cervical and lumbar origin caused by skeletal muscle spasm. cyclobenzaprine hydrochloride inhibit tonic α-mononeuronal excitation mediated by descending serotonergic systems by interacting with serotonin receptors at the spinal cord level.

Skeletal muscle relaxant; reduces muscle spasm by depression of brainstem neurons; 5-HT₂ serotonin receptor antagonist.

Características y beneficios

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• Pictogramas: GHS06
• Palabra de señalización: Danger
• Frases de peligro: H301,H312 + H332
• Consejos de prudencia: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P312
• Clasificaciones de peligro: Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Faceshields, Gloves