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Merck

B1125

Sigma-Aldrich

Bathocuproinedisulfonic acid disodium salt

7.2-9.1% purity dry basis (ICP), powder

Sinónimos:

2,9-Dimethyl-4,7-diphenyl-1,10-phenantrolinedisulfonic acid disodium salt, Disodium bathocuproinedisulfonate

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About This Item

Fórmula empírica (notación de Hill):
C26H18N2Na2O6S2
Número de CAS:
Peso molecular:
564.54
Código UNSPSC:
12171500
NACRES:
NA.47

product name

Bathocuproinedisulfonic acid disodium salt, for spectrophotometric det. of Cu, Fe

Análisis

7.2-9.1% dry basis (ICP)

Nivel de calidad

formulario

powder

calidad

for spectrophotometric det. of Cu, Fe

técnicas

titration: 90% using HCLO4 (Dry Basis)

color

white to beige

solubilidad

H2O: 50 mg/mL

idoneidad

suitable for determination of copper

aplicaciones

diagnostic assay manufacturing
hematology
histology

temp. de almacenamiento

room temp

InChI

1S/C26H20N2O6S2.2Na/c1-15-25(35(29,30)31)21(17-9-5-3-6-10-17)19-13-14-20-22(18-11-7-4-8-12-18)26(36(32,33)34)16(2)28-24(20)23(19)27-15;;/h3-14H,1-2H3,(H,29,30,31)(H,32,33,34);;/q;2*+1/p-2

Clave InChI

RNGKZLRAVYPLJC-UHFFFAOYSA-L

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Descripción general

Bathocuproinedisulfonic acid is a strong copper chelator. It is used for the determination of copper and iron in biological samples.

Aplicación

  • Bathocuproinedisulfonic acid disodium salt has been used as a copper chelator for specific assay in Arabidopsis seedlings.
  • It has been used as an electron chain-associated free radical production inhibitor for superoxide dismutase assay in cells.
  • It has been added to the culture media of trypanosomes as a copper chelator for the stabilization of cysteine.

Otras notas

Mixture of isomers

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Minglin Lang et al.
Neurobiology of aging, 34(11), 2604-2612 (2013-07-06)
Disruption of copper homeostasis has been implicated in Alzheimer's disease (AD) during the last 2 decades; however, whether copper is a friend or a foe is controversial. Within a genetically tractable Drosophila AD model, we manipulated the expression of human
Jennifer Lowe et al.
The Journal of biological chemistry, 279(25), 25986-25994 (2004-04-14)
Ccc2p is homologous to the human Menkes and Wilson copper ATPases and is herein studied as a model for human copper transport. Most studies to date have sought to understand how mutations in the human Menkes or Wilson genes impair
Shinya Ogawa et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 909, 34-36 (2012-11-17)
HPLC eluent systems employing acetonitrile and methanol were evaluated for the quantitation of glutathione (GSH) and phytochelatin (PC(n)), a family of peptides implicated in heavy-metal detoxification in higher plants. The detection system is based on the dequenching of copper(I)-bathocuproine disulfonate
Measurement of superoxide dismutase, catalase and glutathione peroxidase in cultured cells and tissue.
Weydert CJ and Cullen JJ
Nature Protocols, 5, 51-66 (2010)
Shinya Ogawa et al.
Analytical chemistry, 81(21), 9199-9200 (2009-09-30)
Reoptimization of analytical conditions was performed for a high-performance liquid chromatographic (HPLC) detection system for Cu(I) chelators based on the dequenching of Cu(I)-bathocuproine disulfonate complexes that occurs in the presence of Cu(I) chelators. The revision corrects for emission and excitation

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