AV31121

Anti-RBPJ antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-CBF1, Anti-IGKJRB, Anti-IGKJRB1, Anti-KBF2, Anti-MGC61669, Anti-RBP-J, Anti-RBPJK, Anti-Recombination signal binding protein for immunoglobulin kappa J region
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• mol peso: 56 kDa
• reactividad de especies: dog, bovine, guinea pig, rabbit, rat, human, horse
• concentración: 0.5 mg - 1 mg/mL
• técnicas: immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• Nº de acceso NCBI: NP_005340
• Nº de acceso UniProt: Q06330
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... RBPJ(3516)

Descripción

Descripción general

RBPJ is a transcriptional repressor that targets notch signaling. Studies have reported that it can activate the K14/vGPCR promoter of Kaposi′s sarcoma-associated herpesvirus (KSHV). Furthermore, RBPJ has also been implicated in the differentiation suppression of myogenic precursor cells.
Rabbit Anti-RBPJ antibody recognizes human, bovine, canine, and mouse RBPJ.

Inmunógeno

Synthetic peptide directed towards the C terminal region of human RBPSUH

Aplicación

Rabbit Anti-RBPJ antibody can be used for western blot (0.25μg/ml) assays.

Acciones bioquímicas o fisiológicas

RBPSUH is a DNA binding protein that activates a full transcriptional response but only demonstrates partial anti-apoptotic activity. RTA-mediated redirection of RBPSUH activity from repression to activation is critical for lytic viral replication.

Secuencia

Synthetic peptide located within the following region: RPHCSAAGAILRANSSQVPPNESNTNSEGSYTNASTNSTSVTSSTATVVS

Forma física

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable