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Merck

A5043

Sigma-Aldrich

Adenosine Deaminase from bovine spleen

Type X, buffered aqueous glycerol solution, ≥130 units/mg protein

Sinónimos:

ADA, adenosine aminohydrolase, Adenosine aminohydrolase

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About This Item

Número de CAS:
Comisión internacional de enzimas:
Número MDL:
Código UNSPSC:
12352204
NACRES:
NA.54

origen biológico

bovine spleen

Nivel de calidad

tpo

Type X

Formulario

buffered aqueous glycerol solution

actividad específica

≥130 units/mg protein

mol peso

32.5-33 kDa

trazas de catión

NH4+: ≤10 μg/mg protein

Nº de acceso UniProt

actividad extraña

alkaline phosphatase ≤0.01%
guanase ≤0.01%
nucleoside phosphorylase ≤0.1%

temp. de almacenamiento

2-8°C

Información sobre el gen

cow ... ADA(280712)

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Descripción general

Molecular weight: 32.5-33 kDa

pI: 4.85

Aplicación

Adenosine Deaminase from bovine spleen has been used in the immobilization on biostrip for stability and catalytic studies.
Adenosine deaminase is useful in various molecular biology assays, such as glycerol release assays . Adenosine deaminase is a potential target for treatments of combined immunodeficiency disease.

Acciones bioquímicas o fisiológicas

Adenosine deaminase is a purine catabolic enzyme which catalyzes the deamination of adenosine and 2′-deoxyadenosine with approximately equal specificity. It is ubiquitous in mammalian tissue, and deficiency in adenosine deaminase has been associated with severe combined immunodeficiency disease.

Definición de unidad

One unit will deaminate 1.0 μmole of adenosine to inosine per min at pH 7.5 at 25 °C.

Forma física

Solution in 50% glycerol, 5 mM potassium phosphate, pH 6.0

Nota de análisis

Protein determined by biuret.

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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