A3487

Clarithromycin

96.0-102.0% (HPLC)

• Sinónimos: 6-O-Methylerythromycin
• Fórmula empírica (notación de Hill): C₃₈H₆₉NO₁₃
• Número de CAS: 81103-11-9
• Peso molecular: 747.95
• Número MDL: MFCD00865140
• Código UNSPSC: 51101500
• ID de la sustancia en PubChem: 329770825
• NACRES: NA.85

Propiedades

• origen biológico: synthetic
• Nivel de calidad: 200
• Análisis: 96.0-102.0% (HPLC)
• formulario: powder
• color: white to off-white
• espectro de actividad antibiótica: Gram-negative bacteria; Gram-positive bacteria
• Modo de acción: protein synthesis | interferes
• temp. de almacenamiento: 2-8°C
• cadena SMILES: O[C@@H]([C@@](O)(C)[C@@H](CC)OC([C@H](C)[C@H]1O[C@@H]2O[C@@H](C)[C@H](O)[C@](C)(OC)C2)=O)[C@@H](C)C([C@H](C)C[C@@](C)(OC)[C@H](O[C@@H]3O[C@H](C)C[C@H](N(C)C)[C@H]3O)[C@H]1C)=O
• InChI: 1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
• Clave InChI: AGOYDEPGAOXOCK-KCBOHYOISA-N

Descripción

Aplicación

Clarithromycin has been used to study its effect on the potassium channel KCNJ5^WT.

Acciones bioquímicas o fisiológicas

Clarithromycin is stable in gastric acid.

Clarithromycin possess bactericidal activity including anti-mycobacterial activity against Mycobacterium leprae, and M.avium complex.

Clarithromycin is a macrolide antibiotic that interferes with bacterial protein synthesis. Clarithromycin is an acid-stable version of erythromycin and is particularly effective against Gram-negative bacteria. It has a short half-life, however its metabolite, 14-hydroxy clarithromycin is nearly twice as active as clarithromycin against certain bacteria.

Envase

100mg

Nota de preparación

Practically insoluble in water, soluble in acetone and methylene chloride, slightly soluble in methanol.

Otras notas

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302
• Consejos de prudencia: P301 + P312 + P330
• Clasificaciones de peligro: Acute Tox. 4 Oral
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable