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A2754

Sigma-Aldrich

Adenosine 5′-diphosphate sodium salt

bacterial, ≥95% (HPLC)

Sinónimos:

ADP sodium salt, ADP

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About This Item

Fórmula empírica (notación de Hill):
C10H15N5O10P2
Número de CAS:
20398-34-9
Peso molecular:
427.20
Código UNSPSC:
41106305
eCl@ss:
32160414
ID de la sustancia en PubChem:
24890690
NACRES:
NA.51

origen biológico

bacterial

Nivel de calidad

300

Análisis

≥95% (HPLC)

formulario

powder

temp. de almacenamiento

−20°C

cadena SMILES

[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(O)=O)C(O)C3O

InChI

1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

Clave InChI

XTWYTFMLZFPYCI-KQYNXXCUSA-N

Información sobre el gen

human ... HSP90AA1(3320) , P2RY1(5028)

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Descripción general

Adenosine 5′-diphosphate (ADP) is an adenine nucleotide involved in energy storage and nucleic acid metabolism via its conversion into ATP by FOF1-ATP synthases. ADP can also be obtained by adenylate monophosphate (AMP) reaction catalyzed by adenylate kinase. ADP is a platelet agonist that is secreted from platelet dense granules. It promotes platelet activation through its interaction with ADP receptors P2Y1 and P2Y12. Upon conversion of ADP to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.

Aplicación

Adenosine 5′-diphosphate sodium salt has been used:
  • as a positive control of platelet aggregation to analyze antiplatelet activity of purified disintegrin by aggregometery.
  • in the preparation of stock solution for a mito stress test.
  • as a positive control in flow cytometry analysis to study the effect of pentameric C-reactive protein (pCRP) and monomeric CRP (mCRP) on the CD62p (P-selectin) expression of platelets.
  • as a platelet agonist to stimulate platelet aggregation.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

nwg

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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