A1651

Adenosine 3′-phosphate 5′-phosphosulfate lithium salt hydrate

≥60%

• Sinónimos: 3′-Phosphoadenosine 5′-phosphosulfate lithium salt, APPS, Active sulfate, PAPS
• Fórmula empírica (notación de Hill): C₁₀H₁₅N₅O₁₃P₂S · xLi⁺ · yH₂O
• Número de CAS: 109434-21-1
• Peso molecular: 507.26 (free acid basis)
• Beilstein: 8181191
• Código UNSPSC: 41106305
• eCl@ss: 32160414
• NACRES: NA.51

Propiedades

• Formulario: powder
• Nivel de calidad: 200
• concentración: ≥60%
• Condiciones de envío: dry ice
• temp. de almacenamiento: −70°C
• InChI: 1S/C10H15N5O13P2S.4Li.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7(27-29(17,18)19)4(26-10)1-25-30(20,21)28-31(22,23)24;;;;;/h2-4,6-7,10,16H,1H2,(H,20,21)(H2,11,12,13)(H2,17,18,19)(H,22,23,24);;;;;1H2/q;4*+1;/p-4/t4-,6-,7-,10-;;;;;/m1...../s1
• Clave InChI: UGODCLHJOJPPHP-AZGWGOJFSA-J

Descripción

Aplicación

3′-Phosphoadenosine 5′-phosphosulfate (PAPS) is used as a universal sulfonate donor for in vivo sulfonation by sulfotransferases. PAPS is used for the sulfation of glycans. PAPS is also useful to study the distribution and function of its biological transporter(s).

Adenosine 3′-phosphate 5′-phosphosulfate lithium salt has been used in a study that cloned and characterized a mammalian lithium-sensitive bisphosphate 3′-nucleotidase inhibited by inositol 1,4-bisphosphate. Adenosine 3′-phosphate 5′-phosphosulfate lithium salt has also been used in a study to assess the golgi-resident PAP-specific 3′-phosphatase-coupled sulfotransferase assays.

Calidad

Major impurities appear to be adenosine 3′,5′-diphosphate, sulfate and ammonia substitution products.

Precaución

Rapid decomposition occurs when exposed to room temperature: up to 17% per day at 37 °C. We ship on dry ice to minimize decomposition in transit.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H315,H319,H335
• Consejos de prudencia: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Clasificaciones de peligro: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órganos de actuación: Respiratory system
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves