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Merck
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A0262

Sigma-Aldrich

Lithium potassium acetyl phosphate

high-energy phosphate donor

Sinónimos:

Acetyl phosphate lithium potassium salt

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About This Item

Fórmula lineal:
CH3COOP(O)(OK)(OLi)
Número de CAS:
94249-01-1
Peso molecular:
184.06
Beilstein:
5689718
Número CE:
304-378-0
Número MDL:
MFCD00002134
Código UNSPSC:
12352204
ID de la sustancia en PubChem:
24890415
NACRES:
NA.32

Nivel de calidad

200

Análisis

≥85% (elemental analysis)

formulario

powder

mp

>300 °C (lit.)

solubilidad

water: 25 mg/mL, clear, colorless

temp. de almacenamiento

−20°C

cadena SMILES

[Li+].[K+].CC(=O)OP([O-])([O-])=O

InChI

1S/C2H5O5P.K.Li/c1-2(3)7-8(4,5)6;;/h1H3,(H2,4,5,6);;/q;2*+1/p-2

Clave InChI

RLQMPLKXFIXRCV-UHFFFAOYSA-L

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Categorías relacionadas

Aplicación

Lithium potassium acetyl phosphate:
  • has been used as a substrate for CpxR (transcription factor) in x-ray crystallography to soak CpxR receiver domain (CpxRRD) crystals to obtain the phosphorylated form
  • may be used as a phosphate (P) donor in a study to screen a wide range of natural and synthetic organic phosphate donors with several enzymes on various hydroxyl?compounds for the improved enzymatic synthesis of phosphate monoesters
  • has been used to set up premixA for in vitro translation reaction

Acciones bioquímicas o fisiológicas

Lithium potassium acetyl phosphate is commonly used as the source for acetyl phosphate. So acetyl phosphate can be used as a suitable alternative to replace inorganic oligophosphates in phosphatase-catalyzed transphosphorylation to reduce inorganic monophosphate by-product formation.

Pictogramas

CorrosionHealth hazard
GHS05,GHS08

Palabra de señalización

Danger

Frases de peligro

H314 - H361

Clasificaciones de peligro

Eye Dam. 1 - Repr. 2 - Skin Corr. 1B

Código de clase de almacenamiento

8B - Non-combustible, corrosive hazardous materials

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Sebastian R Schmidl et al.
Nature chemical biology, 15(7), 690-698 (2019-05-22)
Two-component systems (TCSs) are the largest family of multi-step signal transduction pathways and valuable sensors for synthetic biology. However, most TCSs remain uncharacterized or difficult to harness for applications. Major challenges are that many TCS output promoters are unknown, subject
Juan Andres Imelio et al.
Bio-protocol, 7(16), e2510-e2510 (2017-08-20)
We have developed protocols to generate site-specific variants of the histidine-kinase DesK and its cognate response regulator DesR, conducive to trapping different signaling states of the proteins. Co-expression of both partners in E. coli, ensuring an excess of the regulator
Emiko Kinoshita-Kikuta et al.
PloS one, 10(7), e0132598-e0132598 (2015-07-08)
Hybrid sensor kinase, which contains a histidine kinase (HK) domain, a receiver domain, and a histidine-containing phosphotransmitter (HPt) domain, conveys signals to its cognate response regulator by means of a His-Asp-His-Asp phosphorelay. We examined the multistep phosphorelay of a recombinant
Coilín Boland et al.
Cellular and molecular life sciences : CMLS, 71(24), 4895-4910 (2014-07-12)
Membrane proteins are key elements in cell physiology and drug targeting, but getting a high-resolution structure by crystallographic means is still enormously challenging. Novel strategies are in big demand to facilitate the structure determination process that will ultimately hasten the

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